IJMS, Free Full-Text
Por um escritor misterioso
Last updated 21 setembro 2024
Genomic instability, one of cancer’s hallmarks, is induced by genotoxins from endogenous and exogenous sources, including reactive oxygen species (ROS), diet, and environmental pollutants. A sensitive in vivo genotoxicity test is required for the identification of human hazards to reduce the potential health risk. The somatic mutation and recombination test (SMART) or wing spot test is a genotoxicity assay involving Drosophila melanogaster (fruit fly) as a classical, alternative human model. This review describes the principle of the SMART assay in conjunction with its advantages and disadvantages and discusses applications of the assay covering all segments of health-related industries, including food, dietary supplements, drug industries, pesticides, and herbicides, as well as nanoparticles. Chemopreventive strategies are outlined as a global health trend for the anti-genotoxicity of interesting herbal extract compounds determined by SMART assay. The successful application of Drosophila for high-throughput screening of mutagens is also discussed as a future perspective.
IJMS, Free Full-Text
IJMS, Free Full-Text
IJMS, Free Full-Text
Mpep Substantially Free - Colaboratory
IJMS, Free Full-Text
ISSN 1422-0067 (Online), International journal of molecular sciences
IJMS, Free Full-Text
IJMS, Free Full-Text
IJMS, Free Full-Text
Mastermix Issue 394 - Colaboratory
IJMS Free Full-Text Research Advances In Mechanical, 52% OFF
Ijms Free Full Text Non Invasive Detection Of Extracellular Matrix
IJMS, Free Full-Text
Ijms Free Full Text Recent Advances In Pharmacological 74952
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